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Particular emphasis has been placed on nutraceuticals that act on mitochondrial stability, glutamate excitotoxicity, oxidative burden, and microglial activationeach of which plays a role in the pathogenesis of neovascular and neurodegenerative conditions (Rusciano and Bagnoli, 2023)

*Correspondence: Hitoshi Ando, [email protected] This article was submitted to Pharmacology of Anti-Cancer Drugs, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain