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J., Bernard, C., & Bartolomei, F

Induction of apoptosis through the PKC pathway in cultured dermal papilla fibroblasts

Its proposed mechanisms involve multiple cytoprotective pathways including upregulation of VEGF and growth factors promoting angiogenesis, modulation of the nitric oxide system, activation of the FAK-paxillin pathway for cell migration and tissue repair, interaction with the gut-brain axis affecting dopaminergic and serotonergic systems, and gastroprotective effects against NSAID and alcohol-induced mucosal damage

significantly elevated hepatocyte gene and protein expression including AFP, HNF4A, ALBUMIN, and proteomic and metabolic features that are more aligned with a mature phenotype
