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Moreover, elamipretide is currently undergoing clinical trials, and the preliminary results indicate that its administration in aged mice restored redox homeostasis in muscle, improved mitochondrial quality, and increased exercise tolerance [224]
Post-treatment, the latency to fall was recorded using an accelerating rotarod (starting at 4 rpm and increasing by 0.12 rpm/s to a maximum of 40 rpm) within 5 min
[DOI] [PubMed] [Google Scholar] 7.Lu W, Zheng J
The goals are to maintain pulmonary ventilation and adequate organ perfusion with well-oxygenated blood and to avoid further acidosis until initiation of lipid emulsion therapy
