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The prevalence of MASLD has been escalating rapidly, demonstrating a consistent upward trend year on year, notably among younger individuals [9, 10]

The ion mobility method for measuring lipoprotein subfraction concentrations is unique in its capability of directly determining concentrations of the full lipoprotein spectrum (VLDL, IDL, LDL, and HDL) independent of the particles cholesterol composition (Kanonidou, 2021)

To create translational reporters for scav-5 and scav-6 , we cloned a 2 kb scav-5 promoter with its coding region or a 2 kb scav-6 promoter with its coding region to the upstream of TagRFP and an unc-54 3UTR

Further, these investigational agents are targeting a range of pathological mechanisms including protein homeostasis and neuroinflammation