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However, doses above 2.4 mg showed diminishing returns due to increased gastrointestinal side effects, including nausea, vomiting, and diarrhea

10.3389/fmed.2018.00061 [Google Scholar] Greider CW, Blackburn EH (1985) Identification of a specific telomere terminal transferase activity in tetrahymena extracts

It produced the highest weight loss seen in any phase 2 trial, up to 24% at the highest dose
A novel oral dual amylin and calcitonin receptor agonist (KBP-042) exerts antiobesity and antidiabetic effects in rats