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Description
The active form of MAPKKK phosphorylates MEK1/2 (MAPKK), which in turn phosphorylates ERK1/2 (MAPK), favoring its nuclear translocation and activation of target transcription factors (90)
M.PinedoM.JorrnJ.de La CanalL

doi:10.1007/BF00944786

TP53 gene status is a critical determinant of phenotypes induced by ALKBH3 knockdown in non-small cell lung cancers