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This patent also covers the target patient population and relevant dosing

doi: 10.1128/AEM.00052-18 105 LiJ.TianX.HuaT.FuJ.KooM.ChanW.et al

Effect of creatine supplementation and sleep deprivation, with mild exercise, on cognitive and psychomotor performance, mood state, and plasma concentrations of catecholamines and cortisol

Although the exact etiology of the chronic inflammation process associated with PCOS is not known, it is believed that in adipose tissue, adipocytes and immune cells are the primary sources of cytokine release (Lonardo et al., 2024)
