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This is what the mechanistic description and variant should be based on ARG treated as a form that may change stability or formulation parameters, but requires separate validation

The reaction contained 3.5 mM sulfoxide substrate 4 , 165 mM cyclohexane-1,3-dione in 100 mM KPi buffer, pH 8.0, was initiated by the addition EgtE to a final concentration of 4.0 M (A)

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Continued multidisciplinary research is essential to refine VNS technologies and expand their clinical applicability, ensuring that future applications are grounded in mechanistic insight and optimized for therapeutic specificity