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It has been revealed that GHK has significant inhibitory effects on TGF-1 secretion in vitro and in vivo (Border et al., 1992

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this is due to the increase in size of the boron atoms atomic radius compared to carbon, as well as the fact that boron has a weaker bond strength than carbon

Through this reaction, NNMT links nicotinamide metabolism with methyl group metabolism , impacting both NAD salvage pathways and the epigenetic landscape of cells