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Why Did Isotretinoin Become Popular

A recent study found that the highest driver of a physicians choice of treatment was reduction in percentage of body surface area affected, overall perception of fficacy, and maintenance of response

HepaRG, HepaRG NTCP and PHH cells were cultured in Williams E medium containing GlutaMAX, 5 g/mL human insulin, 50 M hydrocortisone hemisuccinate, 100 IU/mL penicillin, 100 g/mL streptomycin, and 10% fetal bovine serum for HepaRG cells and 5% for PHH (Fetal clone II)

Some clinics set the floor at 16 or 18
