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[DOI] [PMC free article] [PubMed] [Google Scholar] 463.Shi S, Dong H, Chen X, Xu S, Song Y, Li M, et al

[9] In summary, while NAD+ Injection is a broadly applicable metabolic therapy, it should not be used by anyone allergic to it, and it is generally avoided in pregnant women, cancer patients, or those with serious chronic diseases, absent compelling medical rationale

It also means you may have to administer a much larger volume than your research protocol calls for, which can be difficult to manage

At standard concentrations (topical serums at 0.1-1%, injections at 1-4 mg daily), copper peptides deliver copper well below toxic thresholds