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doi: 10.1093/toxsci/67.2.322
Researchers study it for its potential interaction with melanocortin receptors and downstream signaling in pigmentation and appetite models
Recent work further revealed that peroxiredoxin 6 (PRDX6) binds GPX4 via a C47-mediated disulfide interaction to facilitate GPX4 membrane association and ferroptosis protection 100
SIRT6 Silencing Overcomes Resistance to Sorafenib by Promoting Ferroptosis in Gastric Cancer
