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Iba1-Cre transgene was excised, gel-purified, and injected into the pronucleus of fertilized eggs of C57BL/6 J mice

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) has been terminated due to lack of participants and funding for the trial

HEPATOCYTE CELL DEATH MECHANISMS AFTER APAP TOXICITY The mode of cell death after APAP-induced liver injury was controversial initially, since a number of mechanistic steps in the process, such as mitochondrial Bax translocation, release of cytochrome c64,79,88, and nuclear DNA fragmentation32, were similar to that seen during apoptosis (Fig
