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Chatham, J
After the folate cycle, through the interconnection with the methionine cycle involving the entry of cobalamin (vitamin B12), folic acid is again synthesised

Systemic reactions may include gastrointestinal disturbances (nausea, diarrhea, abdominal cramps) when large doses are administered intravenously

Abstract Parkinsons Disease (PD) involves degeneration of dopamine-producing neurons, mitochondrial dysfunction, alpha-synuclein aggregation, neuroinflammation, and gut-brain axis disturbances
