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In particular, hemocompatibility of blood-contacting devices is tested in vitro in accordance with the ISO standard 10993-4 guidelines, and this testing comprises evaluation of thrombosis, the blood coagulation system, the complement system, and multiple effects on platelets and leukocytes [464]

Researchers may study film thickness, dissolution behavior, oral placement context, active-compound distribution, content uniformity, taste masking, packaging, moisture sensitivity, and stability

Therefore it should never be used as a plain IV fluid only used to reconstitute or dilute medications, which typically make the final mixture isotonic

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