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VEGF binds VEGFR2 on endothelial cells triggering proliferation, migration, and tube formation creating new blood vessels
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That means non-injectable GHK-Cu is being evaluated under the 503A interim policy, while injectable-route GHK-Cu should not be described as broadly reopened, FDA-approved, or available through the same pathway

Zhou Q, Ouyang X, Tang H, Wang Y, Hua Y, Li L (2025) Atractylodin alleviates polycystic ovary syndrome by inhibiting granule cells ferroptosis through pyruvate dehydrogenase kinase 4-mediated JAK-STAT3 pathway
