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"Brain-gut Axis and Pentadecapeptide BPC 157." Current Neuropharmacology

Although the mechanism is not entirely clear, lactose increases the transport of calcium through the nonsaturated paracellular pathway, specifically by increasing the volume of distal intestinal fluid, increasing the intercellular space and, consequently, the permeability of the intestinal mucosa

An impairment in monoamine neurotransmitter system such as decreasing of serotonin, dopamine, and noradrenaline as well as neural damage and neural cell loss also have been reported to take role in the pathogenesis of depression [40, 41]

The central premise of ischaemic stroke treatment is to limit infarction by rapid and effective recanalization of occluded vessels, leading to reperfusion of the ischaemic semidark zone, and there have been significant advances in the treatment of patients with ischaemic stroke over the last decade or so of research (Malysz-Cymborska et al., 2021)
