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Description
Trx in particular has been shown to regulate several signal transduction pathways involving ASK-1, NF-B, PTEN, and AP-1 and the NLRP-3 inflammasome (41), suggesting that the switch between thiol/disulfide is a critical component of intracellular signaling machinery that turns protein targets on/off to activate or deactivate specific signaling pathways
This underscores direct involvement of TP53 in SCA3 pathogenesis
A large family of class III plant peroxidases
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