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A total of 85 healthy women, aged 4365 years old, were randomly assigned to the collagen group ( n = 42), which received supplementation of 5 g daily, or the placebo group ( n = 43) for 12 weeks

[11] [4] Preclinical studies have suggested that combining amylin receptor agonism with GLP-1based therapies produces greater reductions in food intake and body weight than either approach in isolation, and early clinical data from the CagriSema programme (cagrilintide combined with semaglutide) has provided some supporting evidence in humans

Many potential effects are likely but not definitive, so you have to stay flexible and evidence-informed