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Death of oligodendrocytes occurs from around 27 days into cuprizone administration, and reduced oligodendrocyte density is still apparent at 3 weeks, whilst demyelination becomes detectable from around 3 weeks 10,39,54
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Muller PA, Koscso B, Rajani GM, Stevanovic K, Berres ML, Hashimoto D, Mortha A, Leboeuf M, Li XM, Mucida D, Stanley ER, Dahan S, Margolis KG, Gershon MD, Merad M, Bogunovic M (2014) Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility
