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It is worth emphasizing, however, that in further application studies, all the participants confirmed that the applied product did not irritate the skin and exhibit any irritating or sensitizing properties It is also important to consider that in vitro studies expose cells directly to the stimulator, which may increase their sensitivity to the effect

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### **Treatment plan and prior therapy** The documentation must outline that benralizumab is being used as an add-on maintenance treatment, not for acute bronchospasm or status asthmaticus

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3.2.6 Photochemiluminescence assay The photochemiluminescence assay enables precise quantification of O 2 - scavenging capacity through controlled photochemical generation and luminescence detection

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Andrews N, Stowe J, Kirsebom F, Toffa S, Rickeard T, Gallagher E, et al

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