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Monitoring vitamin B 12 in women treated with metformin for primary prevention of breast Cancer and age-related chronic diseases

Long-term use creates lasting focus and strength

doi:10.1111/j.1525-139X.2006.00208.x

Without formal reproductive toxicity studies following OECD Test Guideline 414 (prenatal developmental toxicity) and 416 (two-generation reproduction toxicity), we are operating without the data that regulatory science requires before concluding a compound is safe for use during conception attempts or pregnancy
