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doi: 10.1016/j.jcmgh.2015.08.007 23 DelvalleNMDharshikaCMorales-SotoWFriedDEGaudetteLGulbransenBD

Nature Reviews Cancer (2008) 9
If you plan to resume, restart at the full dose rather than titrating back up, since the break period allows receptor resensitization

Therefore, it is not appropriate most -- especially those who are pregnant, breastfeeding, have active cancer, or certain metabolic conditions
