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Another study has indicated that TcdB from epidemic NAP1/RT027 strains induced the dysfunctional stem cell state in both mice and human colonic organoids without binding to FZD1/2/7, instead it maintained the ability to interact with CSPG4 and Nectin-3 (Mileto et al., 2020)

Hicks et al., 2008), it has been proposed that activating proteins serve to orient the active site of the enzyme near the surface of the negatively charged membrane

SUGAR-DEPENDENT1 encodes a patatin domain triacylglycerol lipase that initiates storage oil breakdown in germinating Arabidopsis seeds

Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-N-oxide
