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For instance, pH-sensitive liposomes and hypoxia-activated prodrugs can selectively release ferroptosis inducers (e.g., erastin or RSL3) in the acidic or hypoxic TME, minimizing systemic exposure (282)

In this study, PCA was used to analyse the correlations between thirteen probiotic characteristics (low pH tolerance at 2 and 3, bile salt tolerance at concentration of 0.5%, 1.0%, and 1.5%, auto-aggregation, co-aggregation with four pathogens, cell surface hydrophobicity, bile salt hydrolase, antioxidant activity) and yeast strains isolated from kombucha produced in New Zealand

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TMAO reduction therapy Recent studies have identified many clinical links among the TMAO pathway and adverse CVD outcomes (Jin et al., 2021)