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Rohou A, Grigorieff N

Multi-target combination therapy for CHB has emerged as a consensus approach

Resistance to growth hormone is seen in Laron syndrome and in mutations in IGF1 and IGF1R while decreased bioavailability of IGF1 is seen in ALS deficiency and PAPPA2 deficiency

The review may inevitably incorporate lower-quality studies, potentially impacting the reliability of the conclusions
