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Bortezomib is FDA approved for the treatment of relapsed and refractory multiple myeloma more than 10 years ago 78
Calculate how long it will take to reach 90% of the steady state plasma drug level given a drugs elimination half-life
After being stimulated by fibrogenic factors, HSCs change from vitamin A-storing latent cells to active cells that resemble myofibroblasts, depositing an abundance of ECM, especially type I collagen
PMID: 15673999)
