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2 Ferroptosis and its link to DCM Ferroptosis is a form of programmed cell death driven by the excessive accumulation of iron ions within cells, triggering the Fenton reaction, activating oxidative stress, and disrupting lipid metabolism, ultimately leading to cellular demise (22, 23)
& Mohler, H
As indicated above the elevated NADH resulting from the metabolism of ethanol results in the impairment of hepatic gluconeogenesis from lactate, alanine (and other amino acids), and glycerol
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