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Lactate metabolism in neurodegenerative diseases

Inspired by the chemotactic behavior of organisms in nature, researchers engineered artificial micro/nanomotors capable of chemotactic movement mimicking microscopic organisms 30,31,32

These experimental data demonstrated that the EGCG-Zn suppository exhibited good biocompatibility and an acceptable safety profile during the evaluated treatment period, supporting its potential suitability for localized rectal administration

Evaluation of SHC4H+h v -induced mitophagy regulation and mitophagy stress Hypoxia and elevated ROS levels in mitochondria trigger cellular mitophagy, where HCQ disrupts lysosomal function by raising lysosomal pH, hindering enzymatic activity, thus blocking autophagosome degradation and inducing mitophagy stress (Fig