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In NDDs, microglia detect pathological signals through pattern recognition receptors (PRRs), including damage-associated molecular patterns (DAMPs) such as amyloid- (A) aggregates, hyperphosphorylated Tau proteins, neuronal debris and mitochondrial DNA (mtDNA) in AD (22,23)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 348.Cielen N., Heulens N., Maes K., Carmeliet G., Mathieu C., Janssens W., Gayan-Ramirez G
