glutathione protects cancer cells Human cancer-associated fibroblasts enhance levels and antagonize drug-induced prostate cell death Application of glutathione depletion in

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In contrast, DRD3 gene hypermethylation is associated with decreased expression, and dysregulated methylation of COMT and DRD3 genes is linked to both schizophrenia risk and sex-specific differences ( COMT methylation has also been detected in saliva samples from schizophrenia and bipolar disorder patients, suggesting potential cross-tissue relevance and supporting the development of non-invasive biomarkers ( In addition, DNA methylation abnormalities extend to the endocannabinoid system (ECS), further implicating epigenetic regulation in schizophrenia

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