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[DOI] [PubMed] [Google Scholar] 62.Lin C-W, Chen C-Y, Cheng S-J, Hu H-T & Hsueh Y-P Sarm1 deficiency impairs synaptic function and leads to behavioral deficits, which can be ameliorated by an mGluR allosteric modulator

Cell 117 , 495502 (2004)

Elevated NAD+ levels activate sirtuins, particularly SIRT1, which are NAD+-dependent deacetylases that regulate numerous metabolic processes including fat oxidation, glucose metabolism, mitochondrial biogenesis, and cellular stress responses
