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Semax CNS Biology: MC4R-BDNF Neurotrophin and GR Mechanisms Semaxs CNS biology is direct the peptide crosses the blood-brain barrier efficiently following intranasal administration (bioavailability ~80% via olfactory epithelium CSF route), with peak CSF concentrations at 1525 minutes

Acknowledgements Authors wish to thank Molecular Medicine Department and also Pharmaceutical Sciences Research Center of Shiraz University of Medical Sciences

These results support development of small molecule NNMT inhibitors as therapeutics to reverse diet-induced obesity and validate NNMT as a viable target to treat obesity and related metabolic conditions

But in recent years there has been a boom in interest in using peptides for therapeutic purposes, from weight loss to anti-ageing and injury recovery