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Phase I metabolic products may be further metabolized Phase II reactions often use phase I metabolites can catalyze the addition of other groups, e.g
10.1038/s41423-021-00807-4 [DOI] [PMC free article] [PubMed] [Google Scholar] 318.Pacheco Y, Valeyre D, El Jammal T, Vallee M, Chevalier F, Lamartine J, et al

Brelstaff, J., Tolkovsky, A

This is a normal part of the process and typically fades quickly
