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Risk assessments for human inhalation toxicity based on traditional animal studies generally include a safety factor of 25 to account for uncertainties related to interspecies (animal-to-human: 2.5-safety factor) and inter-individual (human-to-human: 10-safety factor) variabilities ( in vitro PoDs from MucilAir readouts (i.e., TEER, lactate dehydrogenase leakage and resazurin metabolism analyses) with dosimetry information obtained from a computational fluid-particle dynamics (CFPD) model (Ramanarayanan et al., 2022)

The water is removed under vacuum at low temperatures, leaving behind a stable cake or powder that resists degradation far better than a liquid solution

[DOI] [PubMed] [Google Scholar] 35.Gawe S., Wardas M., Niedworok E., Wardas P

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