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In a Chinese study, researchers found that in addition to glycolysis, metformin can also interfere with fatty acid synthesis amino acid metabolism, and other processes in tumor cells, which are also crucial for the growth and survival of tumor cells

The analytes were eluted by the mobile phase containing (A) 0.1% TCA adjusted to pH 1.7 with 1 mol/L NaOH and (B) ACN with the gradient elution as follows: 06 min, 1935% (B)

Acknowledgements This manuscript was completed with project funding from Changxiang Li, Qingguo Wang and Zilin Ren
