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J Biol Chem 281 , 1453746 (2006)

Moreover, LSC-derived exosomes enhance the expression of adipolysis genes ATGL and HSL in adipocytes, promoting lipolysis and releasing free fatty acids (FFAs)

Tyrosinemia is an inherited disorder in a single pathway involving mutations in one of three distinct enzymes involved in tyrosine degradationfumaroylacetoacetate hydrolase (EC 3.7.1.2) (Grompe et al., 1994), TAT (James et al., 2005) or 4-hydroxyphenylpyruvate dioxygenase (Hpd) (EC 1.13.11.27), the last of which is very rare