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Antibiotics profoundly disrupt gut microbiota, transiently reducing IS/pCS production for weeks post-treatment, and phosphate binders such as sevelamer bind IS in the gut, lowering circulating levels independent of microbial production changes

Notably, decreased -3 PUFAs/monounsaturated fatty acids and reduced desaturation indices in lipid rafts emerge early in entorhinal and frontal cortices, suggesting lipid microenvironment alterations precede classical pathological deposition (116)

Physiol Plant 100:241254 [Google Scholar] Frankel EN (1996) Antioxidants in lipid foods and their impact on food quality

Expression of aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator messenger ribonucleic acids and proteins in rat and human testis
