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On the one hand, this activation promotes the production of inflammatory factors, triggering an inflammatory response to combat the virus
Reduction of protein disulfide isomerase results in open conformations and stimulates dynamic exchange between structural ensembles
For instance, complex I inhibition by metformin in pancreatic CSCs led to their apoptosis, but no cytotoxic effect was brought about in FP-CSCs when pyrvinium pamoate inhibited complexes I and II
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