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Traditional payloads, such as microtubule inhibitors and DNA-damaging agents, have been effective but come with significant limitations in terms of resistance and off-target toxicity
doi: 10.1038/s41572-019-0097-9 2 CallaghanBCHurJFeldmanEL
Individuals who lack intrinsic factor (IF) are especially prone to pernicious anemia and neurological problems
