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The Harding lab work is real and interesting but is hypothesis-generating research, not clinical efficacy data

They reported 95% clearance of AN of axillae after seven sessions and concluded that long-pulsed alexandrite laser can effectively and safely treat acanthosis nigricans of the axillae.[11,27,36] Treatment of acanthosis nigricans maligna There is a case report of AMN regressing rapidly following treatment with cyproheptadine despite progression of metastatic disease