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While this has garnered substantial information on where active canonical Wnt signaling is required during development and regeneration, much of the identity of Wnt secreting cells and what combinations of Wnt and Frizzled members are responsible for activating Wnt/-catenin signaling in specific developmental and regenerative processes still remain unknown (Figure 2)

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Novel strategies for effective brain targeting Effective treatment approaches against brain disorders like AD, PD, depression, epilepsy, schizophrenia, and migraine are not available yet
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