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We found that APR-017 or LCS3 treatment induced an increased level of ROS and a decreased level of GSH (presented as the ratio of GSH to oxidized form, GSSG) in VRK2-KO cells, but not VRK2-WT cells (Fig

An article in Pharmacia laid out: "Curcumin is comparable to metformin." It detailed a study where curcumin was used to treat PCOS in rats
J Psychopharmacol 23 : 287294

CYP3A4, the most abundantly expressed in liver, is involved in the metabolism of over 50% of clinically used drugs (Figure 63A)
