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6 Discussion With the application and development of chemotherapy, the emergence of tumors chemoresistance and side-effects poses a significant challenge in the treatment of malignant tumors

MMW Fortschr Med

This includes considering the desired level of basal expression determined by the vectors promoter (Lozano Terol et al., 2021)

A 2009 study, conducted by the European Organisation for Rare Diseases, surveyed 414 families of EDS patients from five countries and found that the average delay to an EDS diagnosis was four years for men but 16 years for women
