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Binding to Gpr19 activates PI3K/AKT signaling pathway, leading to AKT phosphorylation at Ser 473 [156]

Bischof K, Moitzi D, Stoop R, et al
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In human embryos, just prior to and during the second half of the pronuclear stage and before entering the first mitotic division, demethylated paternal DNA is immediately re-methylated, together with de novo H3-K9 tri-methylation [10]
