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A systematic review published in International Psychogeriatrics examined 43 studies investigating the association of vitamin B12 and cognitive impairment or dementia and 17 studies reporting the efficacy of vitamin B12 therapy for these cognitive conditions
The T allele of rs2071746 is linked to reduced gene expression, potentially leading to higher free heme concentration and stress-induced erythropoiesis, consequently increasing Hb F levels

Care 18 , 372382 (2020)

10.3390/antiox11112173 118 HarcrovP.LomozovZ.KallivretakiM.KarlckovJ.KuceraR.MladenkaP