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10.1055/s-2007-996108 [DOI] [PubMed] [Google Scholar] 17
GPX4 is currently the only known enzyme that can effectively eliminate lipid peroxides from the membrane and is widely recognized as the core negative regulator of ferroptosis whose functions depends largely on the intracellular level of GSH (Figure 3B), indicating that it likely enhances the function of this GSH- GPX4 defense system to resist ferroptosis
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Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model
