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That is a signal, not a final answer

Orotate phosphoribosyltransferase gene polymorphism predicts toxicity in patients treated with bolus 5-fluorouracil regimen

It disrupts the balance of the tumor immune microenvironment by synergistically regulating immune cells, precisely antioxidant, and relieving immune suppression, forming a microenvironment conducive to anti-tumor immunity, thereby exerting a powerful cancer immunotherapy effect and showing good biocompatibility and tumor accumulation characteristics [427, 428]

Ubiquitination during plant immune signaling
