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doi:10.1016/j.jep.2007.11.038

Presumably, the dry skin results from normalization of differentiation and proliferation of the keratinocytes and loosening of their adhesion to one another, thereby resulting in flaky skin.[25] One can also speculate that a topical retinoid would also bind to the sebocytes retinoid receptors, resulting in decreased sebum production, but evidence has yet to exclusively illustrate that topical retinoids are sebosuppressive.[26] Both tazarotene and tretinoin have been reported to reduce facial pore size

It should not be chewed, crushed, or broken

Savic D, Ball V, Curtis MK, et al
