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Research indicates that the GLP-1 receptor agonist exenatide (Exendin-4) exhibits significant anti-inflammatory effects in neurodegenerative diseases, can clear pathological -syn through autophagy, and alleviates motor deficits induced by PD [165, 166]

Nitric oxide (NO) is a free radical gas molecule produced endogenously from L-arginine, oxygen, and NADPH by an enzyme nitric oxide synthase (NOS) [139]